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Take her for a few short trips now. It could be she will be fine. We let ours travel in a cage and they can go for several hours without problems. If you can get away without medication all the better. A few treats underway might be good. 4 hours should be no problem. Make sure she is protected, has a harness on and dont let her out of the car without being on the leash. She might panic and run off. At your destination take her in on the leash, watch she doesnt escape.