We have a similar problem with Daisy and Rocky. Daisy is ALL play and Rocky gets irritated sometimes. There's really never been a fight but he'll definitely let her know when he's had enough. There have been a few times where I've put Daisy outside or inside away from Rocky (only has to be for a few mins) if she just won't quit messing with him, but most of the time they're fine. They've been like that since we got them from the humane society together. I would say Snoopy will probably let Squeeker know if he's had enough. It sounds like Squeeker needs some of her excess energy run off. Maybe an extra walk for her would help release some of it and give Snoopy a break.