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Discussion Starter · #1 ·
Hi, all! $1,600 and two months later the (now) premature diagnosis of Cushings is heading out the window! Vet did ACTH stim test to get a pre-treatment level and results came out, unexpectedly, in the "questionable" range. Then on to a low dose dex test -- just got off the phone with the vet. Results fell solidly in the normal range. Very, very frustrating which, as I've read, is the route lots of folks go through. My vet is going to call the internist this week and pick his brain for where we go from here, particularly his thoughts on "atypical Cushings". The vet and I are leaning towards treating liver changes with the milk thistle/Sam-E/Vitamin E protocol and then running labs again in six months and, if necessary, another ultrasound. Meanwhile, Maggie is being her stubborn, beagle self, seemingly oblivious to her pot belly!
 

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Well, it's good to hear Maggie's doing well right now. Hopefully you'll be able to nail down the actual problem soon!
 

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How frustrating and stressful for you. I hope you find something soon. Maggie and I are sending good thoughts your way.
 

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Judy, I know how it must feel for you and Maggie, with all those tests and everything. But at least Maggie is still doing okay right now, and that's good to hear. Boeing and I will be sending best wishes and thoughts to you both.
 

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Discussion Starter · #5 ·
Judy, I'm sorry that Maggie's diagnosis has been so frustrating. When Amber was diagnosed with Cushings, all of her initial tests came back positive and we went right into treatment. In the meantime, give Maggie lots of belly rubs and kisses on the nose!
 

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Oh man .... that just stinks. I'm glad to hear that it hasn't bothered Maggie to much but sorry that you are on the rollercoaster yet again.

I sure hope that you get some answers soon !!

Hugs to you and belly rubs for Maggie !!
 

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Discussion Starter · #7 ·
Sorry to here the test results came back confusing. Beagles just don't do things simple, do they? At least Maggie is her normal self for the time being.

Belly rubs from us!
 

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Judy, we hope they get to the bottom of Maggies problem soon. We are thinking of you both.
 

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Judy,l

What a dissapointment...thinking you know then finding out that you don't.

The good news is that Maggie is feeling O.K. Please give her some love from Henry and I.
 

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Discussion Starter · #10 ·
That has to be so frustrating! I hope a definite diagnosis can be made soon. In the meantime, if you do try the milk thistle, vitamin E, Sam-E therapy, I hope it works as well for Maggie as it did for my Traveler. Good luck!
 

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Well, this is sort of a good news/bad news report, isn't it? Sure hope your vet can get to the cause of Maggie's problems.
 

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Haven't posted for a while, but felt I might put in my 'two cents' on your 'Cushings' diagnosis.

We recently went through this with our 10 year old Sam. Just as we thought we would begin the treatments for Cushings, the vet tried one last set of blood work to evaluate his thyroid levels. It turns out that his levels were lower than they should be (Hypothyroidism) and he has been on thyrozine for the last 4 months with great results.

While one of his liver levels remains slightly elevated (but much lower than when we started this journey), we will continue this course and evaluate the thyroid and liver again in 2 months. In the meantime, Sam has returned to his usual self.

Not sure if this will work for your situation, but it might be worth asking about.
 

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Hey there Judy
Boy that would be frustrating!! From working in the medical field I know that it can be SOO tough to diagnosis some diseases/conditions, and it would be even tougher with animals/pets that cant tell you what hurts, etc!!!
I am thinking of you and your Maggie-hoping you can find something to "deflate" that pot belly soon and keep Maggie running around being her usual beagle self!
Judi and the gang
 

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Discussion Starter · #14 ·
Just a quick update -- thanks to everyone for your suggestions/thoughts/concerns -- I really do appreciate your input. KTV -- Maggie's thyroid is tested every six months. She was hypothyroid at one point and was on meds. Then she was on too much and next couple of tests were normal so now no meds, just re-testing. Present plan is to add the Vitamin E/SAM-e/milk thistle trio to her daily pill regimen and then, in six months, re-do labs and another ultrasound (hey, I get a discount if two are done in one year ... :rolleyes: ). She seems to be feeling pretty good -- wants to play and I can push her to walk on most days. Also got a new med to keep at home to use with the valium if she has another attack when the vet's office is closed(seems almost inevitable). It is a tranquilizer so will be interesting to see what happens.
 

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Our Tippi has the exact same symptoms as Maggie and I have been researching since 2003 trying to help her. Thank heaven for Beagle World. Her thyroid tests came back normal and the Cushings test was borderline. She was on Thyroid meds for 2 months with no change. Next is the ACTH stim test which I am praying will tell us something. Our Vet is really stumped. Any additional info you could give me would be greatly appreciated.
 

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Discussion Starter · #16 ·
Hi, Lora! I just read your intro about Tippi -- a huge welcome from to BW (from one Floridian to another!) -- glad you found us. Everyone here has a wealth of compassion and knowledge. You mentioned in your intro that you were going to have the ACTH at UFL -- they have a great reputation. Hopefully, you have hooked up with an internist there who can consult with your vet. Up here in Tampa, I have that relationship through Florida Veterinary Specialists. I am a bit confused about Tippi's testing sequence -- you mentioned that the Cushings' test was borderline but now she is going to have the ACTH. Was it a urine test or maybe the low dose dex test that she already had? Recently I found a fantastic Cushings website/on-line group. You have to join (for free) in order to access their research articles but it is well worth it. I don't post -- just read other posts and printed out and read every article they have. Not sure my vet always appreciates my questions but I ask them anyway based on what I have read and at least the terminology the internist uses makes more sense to me. The website for the group is:
http://www.caninecushings.net/?s=3a3b3a714862b1ef52f9785677910f90&
After joining, click on "forums" at the top, then go to "Important Information & Resources". There is a post called "Veterinary Endocrinology Symposium Proceedings" with an article from a conference held this past fall -- pg. 14 has a sub-article on testing by Dr. Feldman, one of the leaders in the field. Before you have the expense of the ACTH, you might want to ask some questions.
I am sorry you are a member of the "hard-to-diagnose" group but at least you are not the sole member! Please feel free to PM me.
 

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A big BW howdy from Miss Shiloh and me too, Lora and Tippi. You will find I am very chatty, and posted longer to you also in the Introduction section.
 
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